What is the link between thrombosis and tumors?

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The link between tumors and blood clots was described in 1865 by the French physician Armand Trousseau, but he could not provide a scientific explanation. In more recent times, the relationship has become clearer and we now know that the link works in two ways: on one hand, patients with cancer have an increased risk of thrombosis and, on the other hand, tumor growth and metastasis can be facilitated by the activation of coagulation and the mechanisms leading to thrombosis.