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The link between tumors and blood clots was described in 1865 by the French physician Armand Trousseau, but he could not provide a scientific explanation. In more recent times, the relationship has become clearer and we now know that the link works in two ways: on one hand,...

Recent studies have shown that cancer patients have 4–6-times the risk of thrombosis compared to the general population, and an episode of thrombosis in these patients has a negative impact on their survival. The risk is highest in the first few months after a cancer...

The incidence of thrombosis in cancer patients varies with the type and stage of the tumor. It is highest in patients with tumors of the pancreas, stomach, brain, kidneys, uterus, lungs and ovaries, especially if the disease is advanced. Breast cancer has a lower risk of...

The pathogenesis of thrombosis in cancer is complex and multifaceted. There are general factors, factors linked to the body’s inflammatory response to the tumor and certain specific properties of the cancer cells, which release substances that inappropriately activate blood...

Venous thrombosis has far-reaching effects on a patient’s quality of life and prognosis. Thrombosis is, in fact, the second cause of death – after the tumor itself – among these patients, with often dramatic consequences on the quality of their lives and their life...

Preventing venous thrombosis in patients with cancer is fundamental for several reasons: once the thrombosis has happened it is hard to manage the anticoagulant therapy because of the substantial risk of hemorrhage, and anticoagulants are not very effective and raise the risk of...